LocalOps

Science Model

Can I Run ESM3 Open Locally?

Simulate & generate biology

System Configuration

Configure your hardware to check compatibility

VRAM12GB
Bandwidth504 GB/s
TDP285W
System RAM32GB
Typededicated

Compatibility Result

Based on your selected hardware

Incompatible
VRAM Usage63.7GB / 12GB
Est. SpeedN/A (Non-Text)
Context (KV)
N/A
Disk Space
58.8 GB
Your hardware does not meet the minimum memory requirements to run this model even with offloading.

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